(AP) -- TAMPA, Fla. (AP) - Tony Pike threw two touchdown passes before spraining his left wrist and backup Zach Collaros ran 75 yards for a score to lead No. 8 Cincinnati to a 34-17 victory over No. 21 South Florida on Thursday night.

Collaros squirted through an opening in the middle of the defense for the long touchdown three plays after replacing Pike. The senior was injured late in the first half, then left after being hit as he released an incomplete pass on Cincinnati's first possession of the second half.

Pike threw scoring passes of 3 and 8 yards to Armon Binns in the second quarter, helping the Bearcats (6-0, 2-0 Big East) to a 17-10 halftime lead over South Florida (5-1, 1-1).

(Copyright 2009 by The Associated Press. All Rights Reserved.)

(Copyright ©2009 by The Associated Press. All Rights Reserved.)